Endocrine Abstracts

Introduction A few adrenal masses may elude characterization on cross-sectional imaging and remain indeterminate. These include lipid-poor adenomas, adrenal metastases and carcinomas and phaeochromocytomas. It is important to distinguish between them, as phaeochromocytomas can be fatal if operated without preoperative blockade. Their clinical spectrum varies, from dramatic symptoms and signs including paroxysmal headache, flushing, diaphoresis, hyper...

Introduction A few adrenal masses may elude characterization on cross-sectional imaging and remain indeterminate. These include lipid-poor adenomas, adrenal metastases and carcinomas and phaeochromocytomas. It is important to distinguish between them, as phaeochromocytomas can be fatal if operated without preoperative blockade. Their clinical spectrum varies, from dramatic symptoms and signs including paroxysmal headache, flushing, diaphoresis, hyper...

Forty-one vitamin D deficient women (aged 26-75 years, mean 56.2, median 57) were treated with Vitamin D3 (50000 IU/week for 1.5 month and 25000 IU/week for another 1.5 month). Before treatment their serum 25(OH)D was 17.3&pm;6.1 ng/ml (mean&pm;SD) and after treatment 37.0&pm;7.5 (P<0.0001). Their HOMA-IR was 2.2&pm;1.1 before and 2.3&pm;1.1 after (P=NS), serum insulin 9.0&pm;4.2 mIU/l before and 9.6&pm;4.5 after (NS), glucose 96.2&pm;8.2 mg/dl before and...

Introduction: Mixed adenoneuroendocrine carcinoma (MANEC) is a rare tumor of the gastrointestinal tract that consists of a dual adenocarcinomatous and neuroendocrine differentiation. The clinical behavior seems to be influenced by the neuroendocrine component. We report a patient with mixed adenoneuroendocrine carcinoma of cecum who presented 18 years after her initial diagnosis and treatment.Case report: A 59-year-old woman presented with a 3-month hist...

Objectives: The interplay between thyroid function and metabolic state has been studied in many population subgroups. For pregnant women thyroid and metabolic parameters, including glucose homeostasis, are of great importance for a successful outcome. We examined aspects of thyroid function in relation to GDM and BMI in pregnant women referred to our Department.Methods: We studied 520 women during 24th – 32nd gestation week. De...

Aim: Postoperative calcitonin (postCT) is a prognostic factor for disease progression in MTC patients. We evaluated the disease course in patients with persistently elevated post-CT.Methods: Of all MTC patients (n=273) followed-up in our Unit (for 1–37, median 7 years), 140 (39.3% men, 67.1% sporadicMTCs) had persistently elevated postCT (≥2.0 pg/ml). Clinical and biochemical data were recorded. Patients were classified in four groups...

BackgroundFollowing the 4th edition of WHO classification of thyroid tumors several pathologic entities were reclassified, mainly as a means of de-escalating addressed therapy. We herein present two rare types of thyroid cancer, hyalinizing trabecular tumor (HTT) and Warthin-like papillary carcinoma (WL-PTC).Cases presentationA 64-year-old female patient presented with an ultrasonographic 1.92 × 1.11 cm ...

Background: Follicle stimulating hormone (FSH), a dimeric glycoprotein hormone, stimulates Sertoli cell proliferation and spermatogenesis in males. Azoospermia is defined as the absence of sperm in the ejaculate. The majority of patients with non-obstructive azoospermia have high FSH levels. Isolated FSH deficiency has been reported in a few patients.Case Presentation: A 22-yr-old, 172-cm-tall male presented with azoospermia. He was born at full term wit...